Munster centre Tom Farrell will receive his first Ireland cap against Japan this weekend.
Head coach Andy Farrell has also named several other changes in the backs, as Craig Casey, Robbie Henshaw, Jacob Stockdale, Tommy O’Brien and Jamie Osborne all start.
Tadhg Beirne has also been included in the squad, after the red card he received in last weekend’s meeting with New Zealand was rescinded.
He’ll be joined in the second row by James Ryan.
Caelan Doris, who returned from injury off the bench last week, is one of four changes to the pack.
Ireland: Jamie Osborne; Tommy O’Brien, Tom Farrell, Robbie Henshaw, Jacob Stockdale; Jack Crowley, Craig Casey; Andrew Porter, Rónan Kelleher, Thomas Clarkson; James Ryan, Tadhg Beirne; Ryan Baird, Nick Timoney, Caelan Doris
Replacements: Gus McCarthy, Paddy McCarthy, Finlay Bealham, Cian Prendergast, Jack Conan, Caolin Blade, Sam Prendergast, Jimmy O’Brien
