In the SSE Airtricity League Premier Division, leaders Shamrock Rovers will bid for their first win of the new season when they play Drogheda United at Tallaght Stadium this evening.
That game kicks off at 8pm.
All of the other domestic games start at 7.45.
Derry City host St Pat's, Bohemians take on Dundalk, Shelbourne go to Sligo Rovers and it's the battle of the newly promoted sides as Galway United host Waterford.
In the First Division, Cork City play UCD, it's Bray Wanderers at home to Longford Town, Wexford meet Cobh Ramblers, Kerry entertain Treaty United and Athlone Town go to Finn Harps.