More 200 medicines are now unavailable to Irish patients, which includes treatment for chest infections, strep-throat, pneumonia and blood pressure.
The analysis compiled by industry experts also found 11 of these medicines are deemed critical by the World Health Organisation.
Penicillin-based antibiotics used to treat bacterial infections are currently 'unavailable from any supplier or source' according to the data compiled by Azure Pharmaceuticals.
In total, 212 medicines are currently unavailable in the country.