Publicans are warning that the move to level three restrictions will see 50,000 job losses in the sector.
Only outdoor sittings of 15 people will be allowed as part of the measures.
No indoor service being allowed will mean many pubs across Mayo and the West will not be able to operate.
The wet pubs were only allowed to reopen two weeks ago after a 6-month closure.
Padraig Cribben from the Vintners Federation says that while Level 3 restrictions refer to pubs remaining open, the reality is that the majority will close as outdoor service limited to 15 customers is not viable for many pubs: